Find Your Path to Lyme Recovery & Support
Discover trusted tools, specialty testing, Lyme-literate practitioners, and healing therapies, all vetted by patients and guided by physicians and experts who understand the complexities of Lyme.
⦿ Thousands of Lyme Patients Reached ⦿
Lyme Advise exists because patients deserve better guidance, clearer answers, and safer pathways to healing. Over the years, we’ve reached thousands of individuals worldwide — each looking for trusted information, practical tools, and a community that truly understands the journey with Lyme and tick-borne diseases. Our platform offers not just education, but empowerment — equipping patients to make informed decisions about their health.
⦿ Lyme-Literate Practitioners & Experts Featured ⦿
Finding the right care can be overwhelming, especially with an illness as complex as Lyme. That’s why we feature only Lyme-literate physicians, specialists, and complementary health providers who have been vetted through both patient feedback and clinical credibility. We’re committed to bridging the gap between patients and practitioners who not only understand Lyme, but also the nuance of coinfections, mold exposure, and immune dysfunction that often come with it.
Could Leucovorin Support Healing in Lyme Disease?
What Autism Research, MTHFR, and Chronic Illness Have in Common
In the autism community, there’s growing interest around leucovorin (also known as folinic acid). Clinical studies suggest it may improve speech, language, and social development in children with folate receptor autoantibodies (FRAA) or cerebral folate deficiency (CFD).
For the Lyme disease community, this is big news. Why? Because folate metabolism and the MTHFR genetic mutation are already a major focus in chronic tick-borne illness. The same folate pathway stress observed in autism also plays a role in how many Lyme patients struggle with detox, cognition, and mitochondrial function. Both groups share challenges with neuroinflammation, detox overload, and methylation problems — making leucovorin a possible bridge between two worlds.
⦿ Exclusive Discounts on Healing Tools & Therapies ⦿
Our partnerships give you access to exclusive discounts on proven supplements, detox tools, red light therapy devices, and more — all carefully selected for safety, efficacy, and chronic illness sensitivity.
⦿ 50,000+ Community Members Across Platforms ⦿
Lyme Advise is more than a resource — it’s a community. With over 50,000 patients, caregivers, and advocates across our platforms, you’ll find connection, shared experiences, real-world advice plus weekly emails designed to help you learn and to help guide your journey.
⦿ 25+ Years of Combined Patient & Practitioner Insight ⦿
Our platform is built on decades of combined insight from both patients who’ve lived through the battle and practitioners who’ve treated complex cases. This fusion of lived experience and clinical guidance ensures you receive information that’s both compassionate and evidence-informed.
Flare vs. Herx:
How to Tell the Difference
One of the most confusing parts of living with Lyme disease is knowing whether you’re having a flare-up of symptoms or a Herxheimer reaction (often called a “Herx”). Both can feel overwhelming, both make you question if your treatment is helping or hurting, and both can look very similar on the surface. But there are important differences that can help you understand what’s happening in your body — and guide your next steps.
Lyme disease is often missed on lab tests because the bacteria can hide in tissues, change form, and even suppress the immune system. That’s why Lyme is considered a clinical diagnosis — based on symptoms, history of tick exposure, and physician expertise. While labs may support the diagnosis, they cannot rule it out. Patients with classic Lyme symptoms should never be dismissed due to negative results. Learn More
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